Effects of clofibrate with androsterone (atromid) and without androsterone (atromid-S) on blood platelets and lipids in ischaemic heart disease.
نویسندگان
چکیده
A mixture of androsterone and clofibrate (atromid) lowers the blood cholesterol and triglycerides (Oliver, 1962). Clofibrate without androsterone (atromid-S) appears to have the same effect on the serum lipids (Oliver, 1963; Hellman et al., 1963). Atromid lowers platelet stickiness (Carson et al., 1963a, b) which is increased in patients with ischamic heart disease (McDonald and Edgill, 1957); the effects of atromid and atromid-S on platelet stickiness have now been compared, and the findings, reported below, are related to changes in the blood lipids.
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References GREEN, K.C. & MARGARETZ, G. (1967) Long-term follow-up of multicentre trial of ethyl-a-p-chlorphenoxyisobutyrate (Clofibrate, 'Atromnid'-S) and Clofibrate Plus Androsterone ('Atromid'). Progress in Biochemical Pharmacology, 2, 378. KATSILAMBROS, BRAATEN, J.B., FERGUSON, D. & BRADLEY, R.F. (1972) Muscular syndrome after clofibrate. New England Journal of Medicine, 286, 1 10. LANGER, T...
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ورودعنوان ژورنال:
- British heart journal
دوره 28 3 شماره
صفحات -
تاریخ انتشار 1966